Ontology highlight
ABSTRACT:
SUBMITTER: Bosco DB
PROVIDER: S-EPMC6011524 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Molecular brain 20180620 1
Microglia have been shown to be of critical importance to the progression of temporal lobe epilepsy. However, the broad transcriptional changes that these cells undergo following seizure induction is not well understood. As such, we utilized RNAseq analysis upon microglia isolated from the hippocampus to determine expression pattern alterations following kainic acid induced seizure. We determined that microglia undergo dramatic changes to their expression patterns, particularly with regard to mi ...[more]