Ontology highlight
ABSTRACT:
SUBMITTER: Wyche TP
PROVIDER: S-EPMC6013059 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Wyche Thomas P TP Ruzzini Antonio C AC Beemelmanns Christine C Kim Ki Hyun KH Klassen Jonathan L JL Cao Shugeng S Poulsen Michael M Bugni Tim S TS Currie Cameron R CR Clardy Jon J
Organic letters 20170322 7
Three new dentigerumycin analogues are produced by Streptomyces sp. M41, a bacterium isolated from a South African termite, Macrotermes natalensis. The structures of the complex nonribosomal peptide synthetase-polyketide synthase (NRPS/PKS) hybrid compounds were determined by 1D- and 2D-NMR spectroscopy, high-resolution mass spectrometry, and circular dichroism (CD) spectroscopy. Both cyclic and linear peptides are reported, and the genetic organization of the NRPS modules within the biosyntheti ...[more]