Ontology highlight
ABSTRACT:
SUBMITTER: Berlanga-Taylor AJ
PROVIDER: S-EPMC6013786 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Berlanga-Taylor Antonio J AJ Plant Katharine K Dahl Andrew A Lau Evelyn E Hill Michael M Sims David D Heger Andreas A Emberson Jonathan J Armitage Jane J Clarke Robert R Knight Julian C JC
EBioMedicine 20180410
<h4>Background</h4>Vitamin D deficiency has been associated with multiple diseases, but the causal relevance and underlying processes are not fully understood. Elucidating the mechanisms of action of drug treatments in humans is challenging, but application of functional genomic approaches in randomized trials may afford an opportunity to systematically assess molecular responses.<h4>Methods</h4>In the Biochemical Efficacy and Safety Trial of Vitamin D (BEST-D), a double-blind, placebo-controlle ...[more]