Ontology highlight
ABSTRACT:
SUBMITTER: Held NM
PROVIDER: S-EPMC6015083 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Held Ntsiki M NM Kuipers Eline N EN van Weeghel Michel M van Klinken Jan Bert JB Denis Simone W SW Lombès Marc M Wanders Ronald J RJ Vaz Frédéric M FM Rensen Patrick C N PCN Verhoeven Arthur J AJ Boon Mariëtte R MR Houtkooper Riekelt H RH
Scientific reports 20180622 1
Activation of brown adipose tissue (BAT) contributes to total body energy expenditure through energy dissipation as heat. Activated BAT increases the clearance of lipids and glucose from the circulation, but how BAT accommodates large influx of multiple substrates is not well defined. The purpose of this work was to assess the metabolic fluxes in brown adipocytes during β3-adrenergic receptor (β3-AR) activation.T37i murine preadipocytes were differentiated into brown adipocytes and we used Seaho ...[more]