Ontology highlight
ABSTRACT:
SUBMITTER: Zhang XC
PROVIDER: S-EPMC6016442 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Chemical science 20160331 7
A supramolecularly tunable chiral bisphosphine ligand bearing two pyridyl-containing crown ethers, (-) or (+)-Xyl-P16C6-Phos, was fabricated and utilized in the Rh-catalyzed asymmetric hydrogenation of α-dehydroamino acid esters and Ir-catalyzed asymmetric hydrogenation of quinolines in high yields with excellent enantioselectivities (90-99% ee). Up to a 22% enhancement in enantioselectivity was achieved by the addition of certain amounts of alkali ions (Li<sup>+</sup>, Na<sup>+</sup> or K<sup>+ ...[more]