Ontology highlight
ABSTRACT:
SUBMITTER: Wong MK
PROVIDER: S-EPMC6016924 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Wong Michael K MK Shawky Sarah A SA Aryasomayajula Aditya A Green Madeline A MA Ewart Tom T Selvaganapathy P Ravi PR Raha Sandeep S
PloS one 20180625 6
The incorporation of the extracellular matrix (ECM) is essential for generating in vitro models that truly represent the microarchitecture found in human tissues. However, the cell-cell and cell-ECM interactions in vitro remains poorly understood in placental trophoblast biology. We investigated the effects of varying the surface properties (surface thickness and stiffness) of two ECMs, collagen I and Matrigel, on placental trophoblast cell morphology, viability, proliferation, and expression of ...[more]