Ontology highlight
ABSTRACT:
SUBMITTER: Wu CZ
PROVIDER: S-EPMC6017251 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20180226 3
A series of bakuchiol derivatives were synthesized and evaluated for their anti-proliferative and the inhibitory activities on SMMC7721 cell line migration using PX-478 as a positive control. The results showed (<i>S</i>,<i>E</i>)-4-(7-methoxy-3,7-dimethyl-3-vinyloct-1-en-1-yl)phenol (<b>10</b>) to have the best activity among the tested compounds, which included PX-478. In addition, compound <b>10</b> showed greater inhibitory activity than that of bakuchiol in the transwell migration and invas ...[more]