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Novel Trifluoromethylcoumarinyl Urea Derivatives: Synthesis, Characterization, Fluorescence, and Bioactivity.

ABSTRACT: A series of novel trifluoromethylcoumarinyl urea derivatives were designed, synthesized, and characterized by ¹H-NMR, 13C-NMR, and HR-ESI-MS. The fluorescence spectra of the target compounds were recorded. The spectra show that most of the title compounds glow green with ?maxem of 500-517 nm, while compounds 5r, 5s, 5u, and 5l (compounds named by authors) glow violet with ?maxem of 381-443 nm. Moreover, the herbicidal and antifungal activities of the synthesized compounds were evaluated for their potential use as pesticides. The results indicate that compound 5f against the caulis of Amaranthusretroflexus and compounds 5j and 5l against the taproot of Digitariasanguinalis are equivalent to the commercial herbicide Acetochlor. Nine of the title compounds are more antifungal than commercial fungicide Carbendazim against Botrytis cinerea.

SUBMITTER: Qiao L

PROVIDER: S-EPMC6017327 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Novel Trifluoromethylcoumarinyl Urea Derivatives: Synthesis, Characterization, Fluorescence, and Bioactivity.

Qiao Lili L Hao Shuanghong S

Molecules (Basel, Switzerland) 20180307 3

A series of novel trifluoromethylcoumarinyl urea derivatives were designed, synthesized, and characterized by ¹H-NMR, 13C-NMR, and HR-ESI-MS. The fluorescence spectra of the target compounds were recorded. The spectra show that most of the title compounds glow green with λmaxem of 500-517 nm, while compounds 5r, 5s, 5u, and 5l (compounds named by authors) glow violet with λmaxem of 381-443 nm. Moreover, the herbic ...[more]

PMID: 29518951

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