Ontology highlight
ABSTRACT:
SUBMITTER: Balta EA
PROVIDER: S-EPMC6020773 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Balta Elli-Anna EA Wittmann Marie-Theres MT Jung Matthias M Sock Elisabeth E Haeberle Benjamin Martin BM Heim Birgit B von Zweydorf Felix F Heppt Jana J von Wittgenstein Julia J Gloeckner Christian Johannes CJ Lie Dieter Chichung DC
Frontiers in molecular neuroscience 20180619
SOX11 is a key Transcription Factor (TF) in the regulation of embryonic and adult neurogenesis, whose mutation has recently been linked to an intellectual disability syndrome in humans. SOX11's transient activity during neurogenesis is critical to ensure the precise execution of the neurogenic program. Here, we report that SOX11 displays differential subcellular localizations during the course of neurogenesis. Western-Blot analysis of embryonic mouse brain lysates indicated that SOX11 is post-tr ...[more]