Ontology highlight
ABSTRACT:
SUBMITTER: Mac Sweeney A
PROVIDER: S-EPMC6021075 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Mac Sweeney Aengus A Chambovey Alain A Wicki Micha M Müller Manon M Artico Nadia N Lange Roland R Bijelic Aleksandar A Breibeck Joscha J Rompel Annette A
PloS one 20180627 6
The use of the tellurium-centered Anderson-Evans polyoxotungstate [TeW6O24]6- (TEW) as a crystallization additive has been described. Here, we present the use of TEW as an additive in the crystallization screening of the nucleotide binding domain (NBD) of HSP70. Crystallization screening of the HSP70 NBD in the absence of TEW using a standard commercial screen resulted in a single crystal form. An identical crystallization screen of the HSP70 NBD in the presence of TEW resulted in both the "TEW ...[more]