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BEL2ABM: agent-based simulation of static models in Biological Expression Language.


ABSTRACT:

Summary

While cause-and-effect knowledge assembly models encoded in Biological Expression Language are able to support generation of mechanistic hypotheses, they are static and limited in their ability to encode temporality. Here, we present BEL2ABM, a software for producing continuous, dynamic, executable agent-based models from BEL templates.

Availability and implementation

The tool has been developed in Java and NetLogo. Code, data and documentation are available under the Apache 2.0 License at https://github.com/pybel/bel2abm.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Gundel M 

PROVIDER: S-EPMC6022644 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Publications

BEL2ABM: agent-based simulation of static models in Biological Expression Language.

Gündel Michaela M   Hoyt Charles Tapley CT   Hofmann-Apitius Martin M  

Bioinformatics (Oxford, England) 20180701 13


<h4>Summary</h4>While cause-and-effect knowledge assembly models encoded in Biological Expression Language are able to support generation of mechanistic hypotheses, they are static and limited in their ability to encode temporality. Here, we present BEL2ABM, a software for producing continuous, dynamic, executable agent-based models from BEL templates.<h4>Availability and implementation</h4>The tool has been developed in Java and NetLogo. Code, data and documentation are available under the Apac  ...[more]

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