Dataset Information

An MR-Based Viscosity-Type Regularization Method for Electrical Property Tomography.

ABSTRACT: Here, a method based on viscosity-type regularization is proposed for magnetic resonance electrical property tomography (MREPT) to mitigate persistent artifacts when it is used to reconstruct a map of electrical properties based on data from a magnetic resonance imaging scanner. The challenges for solving the corresponding partial differential equation (PDE) are discussed in detail. The existing artifacts in the numerical results are pointed out and classified. The methods in the literature for MREPT are mainly based on an assumption of local homogeneity, which makes the approach simple but leads to artifacts in the transition region where electrical properties vary rapidly. Recent work has focused on eliminating the assumption of local homogeneity, and one of the solutions is convection-reaction MREPT that is based on a first-order PDE. Numerical solutions of the PDE have persistent artifacts in certain regions and global spurious oscillations. Here, a method based on viscosity-type regularization is proposed to effectively mitigate the aforementioned problems. Finite difference method is used for discretizing the governing PDE. Numerical experiments are presented to analyze the problem in detail. Electrical properties of different phantoms are successfully retrieved. The efficiency, accuracy, and noise tolerance of the proposed method are illustrated with numerical results.

SUBMITTER: Li C

PROVIDER: S-EPMC6024427 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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An MR-Based Viscosity-Type Regularization Method for Electrical Property Tomography.

Li Changyou C Yu Wenwei W Huang Shao Ying SY

Tomography (Ann Arbor, Mich.) 20170301 1

Here, a method based on viscosity-type regularization is proposed for magnetic resonance electrical property tomography (MREPT) to mitigate persistent artifacts when it is used to reconstruct a map of electrical properties based on data from a magnetic resonance imaging scanner. The challenges for solving the corresponding partial differential equation (PDE) are discussed in detail. The existing artifacts in the numerical results are pointed out and classified. The methods in the literature for ...[more]

PMID: 30042971

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Project description:BackgroundPendelluft, defined as asynchronous alveolar ventilation, is caused by different regional time constants or dynamic pleural pressure variations. The aim of the present study was to propose a simple method to evaluate pendelluft based on electrical impedance tomography (EIT). The efficacy of this method was demonstrated in well-known pendelluft scenarios in 6 patients.MethodsTwo patients with flail chest after accidents, two patients with acute respiratory distress syndrome (ARDS) and two patients with acutely exacerbated obstructive lung disease were prospectively included. EIT measurements were performed before and after surgery (in patients with flail chest, who had video-assisted thoracoscopic surgery with ribs fixation), or at two different levels of positive end-expiratory pressure (PEEP; ARDS patients), or two different time points (obstructive lung disease). Pendelluft was assessed by regional phase shift (defined as time difference between global and regional impedance-time curves) and amplitude differences (defined as the impedance difference between sum of all regional tidal variation and the global tidal variation).ResultsIn patients with flail chest, pendelluft diminished several days after surgery (pendelluft amplitude normalized to tidal impedance variation reduced from 88% to 2% in one patient, 12% to 2% in the other). Increased PEEP reduced the amplitude of pendelluft (from 3% to 0% in one patient, 20% to 2% in the other) but not necessarily the phase shifts (average time differences were <0.1 second for both patients for both ins- and expiration) in ARDS patients. Pendelluft assessment in obstructive lung diseases reflected the change in airway resistance (from 5% to 1% in one patient after broncholytic medication administration, as airway resistance fell from 15 to 11 cmH2O/L/s; from 9% to 35% in the other patient with acute exacerbation, the corresponding airway resistance increased from 15 to 22 cmH2O/L/s).ConclusionsThe proposed EIT-based method can be used to evaluate the degree of pendelluft in dimension of phase shift and amplitude difference.

Dataset Information

An MR-Based Viscosity-Type Regularization Method for Electrical Property Tomography.

Publications

An MR-Based Viscosity-Type Regularization Method for Electrical Property Tomography.

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