Ontology highlight
ABSTRACT:
SUBMITTER: Fan X
PROVIDER: S-EPMC6028726 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Cell research 20180604 7
The cellular complexity of human brain development has been intensively investigated, although a regional characterization of the entire human cerebral cortex based on single-cell transcriptome analysis has not been reported. Here, we performed RNA-seq on over 4,000 individual cells from 22 brain regions of human mid-gestation embryos. We identified 29 cell sub-clusters, which showed different proportions in each region and the pons showed especially high percentage of astrocytes. Embryonic neur ...[more]