Ingested engineered nanomaterials: state of science in nanotoxicity testing and future research needs.

ABSTRACT:

Background

Engineered nanomaterials (ENM) are used extensively in food products to fulfill a number of roles, including enhancement of color and texture, for nutritional fortification, enhanced bioavailability, improved barrier properties of packaging, and enhanced food preservation. Safety assessment of ingested engineered nanomaterials (iENM) has gained interest in the nanotoxicology community in recent years. A variety of test systems and approaches have been used for such evaluations, with in vitro monoculture cell models being the most common test systems, owing to their low cost and ease-of-use. The goal of this review is to systematically assess the current state of science in toxicological testing of iENM, with particular emphasis on model test systems, their physiological

SUBMITTER: Sohal IS 

PROVIDER: S-EPMC6029122 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature