Ontology highlight
ABSTRACT:
SUBMITTER: Auburn S
PROVIDER: S-EPMC6030216 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Auburn Sarah S Benavente Ernest D ED Miotto Olivo O Pearson Richard D RD Amato Roberto R Grigg Matthew J MJ Barber Bridget E BE William Timothy T Handayuni Irene I Marfurt Jutta J Trimarsanto Hidayat H Noviyanti Rintis R Sriprawat Kanlaya K Nosten Francois F Campino Susana S Clark Taane G TG Anstey Nicholas M NM Kwiatkowski Dominic P DP Price Ric N RN
Nature communications 20180703 1
The incidence of Plasmodium vivax infection has declined markedly in Malaysia over the past decade despite evidence of high-grade chloroquine resistance. Here we investigate the genetic changes in a P. vivax population approaching elimination in 51 isolates from Sabah, Malaysia and compare these with data from 104 isolates from Thailand and 104 isolates from Indonesia. Sabah displays extensive population structure, mirroring that previously seen with the emergence of artemisinin-resistant P. fal ...[more]