Ontology highlight
ABSTRACT:
SUBMITTER: Erickson EK
PROVIDER: S-EPMC6033697 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Erickson Emma K EK Farris Sean P SP Blednov Yuri A YA Mayfield R Dayne RD Harris R Adron RA
The pharmacogenomics journal 20180105 4
Astrocytes play critical roles in central nervous system (CNS) homeostasis and are implicated in the pathogenesis of neurological and psychiatric conditions, including drug dependence. Little is known about the effects of chronic ethanol consumption on astrocyte gene expression. To address this gap in knowledge, we performed transcriptome-wide RNA sequencing of astrocytes isolated from the prefrontal cortex (PFC) of mice following chronic ethanol consumption. Differential expression analysis rev ...[more]