Ontology highlight
ABSTRACT:
SUBMITTER: Boyce RM
PROVIDER: S-EPMC6033881 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Boyce Ross M RM Hathaway Nick N Fulton Travis T Reyes Raquel R Matte Michael M Ntaro Moses M Mulogo Edgar E Waltmann Andreea A Bailey Jeffrey A JA Siedner Mark J MJ Juliano Jonathan J JJ
Scientific reports 20180705 1
Molecular techniques are not routinely employed for malaria surveillance, while cross-sectional, community-based parasite surveys require significant resources. Here, we describe a novel use of malaria rapid diagnostic tests (RDTs) collected at a single facility as source material for sequencing to esimtate malaria transmission intensity across a relatively large catchment area. We extracted Plasmodium falciparum DNA from RDTs, then amplified and sequenced a region of the apical membrane antigen ...[more]