Noninvasive PET Imaging of T cells.
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ABSTRACT:
SUBMITTER: Wei W
PROVIDER: S-EPMC6034116 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Publications
Noninvasive PET Imaging of T cells.
Wei Weijun W Jiang Dawei D Ehlerding Emily B EB Luo Quanyong Q Cai Weibo W
Trends in cancer 20180417 5
The rapidly evolving field of cancer immunotherapy recently saw the approval of several new therapeutic antibodies. Several cell therapies, for example, chimeric antigen receptor-expressing T cells (CAR-T), are currently in clinical trials for a variety of cancers and other diseases. However, approaches to monitor changes in the immune status of tumors or to predict therapeutic responses are limited. Monitoring lymphocytes from whole blood or biopsies does not provide dynamic and spatial informa ...[more]
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