Dataset Information

Promoting quality use of medicines in South-East Asia: reports from country situational analyses.

ABSTRACT:

Background

Irrational use of medicines is widespread in the South-East Asia Region (SEAR), where policy implementation to encourage quality use of medicines (QUM) is often low. The aim was to determine whether public-sector QUM is better in SEAR countries implementing essential medicines (EM) policies than in those not implementing them.

Methods

Data on six QUM indicators and 25 EM policies were extracted from situational analysis reports of 20 country (2-week) visits made during 2010-2015. The average difference (as percent) for the QUM indicators between countries implementing versus not implementing specific policies was calculated. Policies associated with better (>?1%) QUM were included in regression of a composite QUM score versus total number of policies implemented.

Results

Twenty-two policies were associated with better (>?1%) QUM. Twelve policies were associated with 3.6-9.5% significantly better use (p?2?=?0.50, p?ConclusionsCountry situational analyses allowed rapid data collection that showed EM policies are associated with better QUM. SEAR countries should implement all such policies.

SUBMITTER: Holloway KA

PROVIDER: S-EPMC6034320 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Publications

Promoting quality use of medicines in South-East Asia: reports from country situational analyses.

Holloway Kathleen Anne KA Kotwani Anita A Batmanabane Gitanjali G Santoso Budiono B Ratanawijitrasin Sauwakon S Henry David D

BMC health services research 20180705 1

<h4>Background</h4>Irrational use of medicines is widespread in the South-East Asia Region (SEAR), where policy implementation to encourage quality use of medicines (QUM) is often low. The aim was to determine whether public-sector QUM is better in SEAR countries implementing essential medicines (EM) policies than in those not implementing them.<h4>Methods</h4>Data on six QUM indicators and 25 EM policies were extracted from situational analysis reports of 20 country (2-week) visits made during ...[more]

PMID: 29976180

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Project description:Background and aimsBesides bananas belonging to the AAA triploid Mutika subgroup, which predominates in the Great Lakes countries, other AAA triploids as well as edible AA diploids, locally of considerable cultural weight, are cultivated in East Africa and in the nearby Indian Ocean islands as far as Madagascar. All these varieties call for the genetic identification and characterization of their interrelations on account of their regional socio-economic significance and their potential for banana breeding strategies.MethodsAn extensive sampling of all traditional bananas in East Africa and near Indian Ocean islands was genotyped with simple sequence repeat (SSR) markers, with particular emphasis on the diploid forms and on the bananas of the Indian Ocean islands, which remain poorly characterized.Key resultsAll the edible AA varieties studied here are genetically homogeneous, constituting a unique subgroup, here called 'Mchare', despite high phenotypic variation and adaptions to highly diverse ecological zones. At triploid level, and besides the well-known AAA Mutika subgroup, at least two other genetically related AAA subgroups specific to this region are identified. Neither of these East African AAA genotypes can be derived directly from the local AA Mchare diploids. However, it is demonstrated that the East African diploids and triploids together belong to the same genetic complex. The geographical distribution of their wild acuminata relatives allowed identification of the original area of this complex in a restricted part of island South-East Asia. The inferred origin leads to consideration of the history of banana introduction in Africa. Linked to biological features, documentation on the embedding of bananas in founding legends and myths and convincing linguistic elements were informative regarding the period and the peoples who introduced these Asian plants into Africa. The results point to the role of Austronesian-speaking peoples who colonized the Indian Ocean islands, particularly Madagascar, and reached the East African coasts.ConclusionsUnderstanding of the relations between the components of this complex and identifying their Asian wild relatives and related cultivars will be a valuable asset in breeding programmes and will boost the genetic improvement of East African bananas, but also of other globally important subgroups, in particular the AAA Cavendish.

Dataset Information

Promoting quality use of medicines in South-East Asia: reports from country situational analyses.

Background

Methods

Results

Publications

Promoting quality use of medicines in South-East Asia: reports from country situational analyses.

Similar Datasets

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