Ontology highlight
ABSTRACT:
SUBMITTER: He C
PROVIDER: S-EPMC6037732 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
He Chengyong C Qiu Yang Y Han Peiyu P Chen Yuanyuan Y Zhang Liyin L Yuan Quan Q Zhang Tianying T Cheng Tong T Yuan Lunzhi L Huang Chenghao C Zhang Sheng S Yin Zhenyu Z Peng Xian-E XE Liang Dong D Lin Xu X Lin Yuchun Y Lin Zhongning Z Xia Ningshao N
Cell death & disease 20180709 7
Hepatitis B virus X (HBx) protein contributes to the progression of hepatitis B virus (HBV)-related hepatic injury and diseases, but the exact mechanism remains unclear. Protein phosphatase 2 A (PP2A) is a major serine/threonine phosphatase involved in regulating many cellular phosphorylation signals that are important for regulation of cell cycle and apoptosis. Does HBx target to PP2A-B56γ and therefore affect HBx-induced hepatotoxicity? In the present study, the expression of B56γ positively c ...[more]