Ontology highlight
ABSTRACT:
SUBMITTER: Dinges MM
PROVIDER: S-EPMC6040582 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Dinges Meredith M MM Lytle Christian C Larive Cynthia K CK
Analytical chemistry 20180307 6
The large intestine (cecum and colon) is a complex biochemical factory of vital importance to human health. It plays a major role in digestion and absorption by salvaging nutrients from polysaccharides via fermentation initiated by the bacteria that comprise the gut microbiome. We hypothesize that the intestinal epithelium absorbs a limited number of luminal metabolites with bioactive potential while actively excluding those with toxic effects. To explore this concept, we combined <sup>1</sup>H ...[more]