Dataset Information

Mapping visuospatial attention: the greyscales task in combination with repetitive navigated transcranial magnetic stimulation.

ABSTRACT:

Background

Visuospatial attention is executed by the frontoparietal cortical areas of the brain. Damage to these areas can result in visual neglect. We therefore aimed to assess a combination of the greyscales task and repetitive navigated transcranial magnetic stimulation (rTMS) to identify cortical regions involved in visuospatial attention processes. This pilot study was designed to evaluate an approach in a cohort of healthy volunteers, with the future aim of using this technique to map brain tumor patients before surgery. Ten healthy, right-handed subjects underwent rTMS mapping of 52 cortical spots in both hemispheres. The greyscales task was presented tachistoscopically and was time-locked to rTMS pulses. The task pictures showed pairs of horizontal rectangles shaded continuously from black at one end to white at the other, mirror-reversed. On each picture the subject was asked to report which of the two greyscales appeared darker overall. The responses were categorized into "leftward" and "rightward," depending on whether the subject had chosen the rectangle with the darker end on the left or the right. rTMS applied to cortical areas involved in visuospatial attention is supposed to affect lateral shifts in spatial bias. These shifts result in an altered performance on the greyscales task compared to the baseline performance without rTMS stimulation.

Results

In baseline conditions, 9/10 subjects showed classic pseudoneglect to the left. Leftward effects also occurred more often in mapping conditions. Yet, calculated rightward deviations were strikingly greater in magnitude (p?ConclusionThe greyscales task, in combination with rTMS, yields encouraging results in the examination of the visuospatial attention function. Future clinical implications should be evaluated.

SUBMITTER: Giglhuber K

PROVIDER: S-EPMC6042394 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Publications

Mapping visuospatial attention: the greyscales task in combination with repetitive navigated transcranial magnetic stimulation.

Giglhuber Katrin K Maurer Stefanie S Zimmer Claus C Meyer Bernhard B Krieg Sandro M SM

BMC neuroscience 20180711 1

<h4>Background</h4>Visuospatial attention is executed by the frontoparietal cortical areas of the brain. Damage to these areas can result in visual neglect. We therefore aimed to assess a combination of the greyscales task and repetitive navigated transcranial magnetic stimulation (rTMS) to identify cortical regions involved in visuospatial attention processes. This pilot study was designed to evaluate an approach in a cohort of healthy volunteers, with the future aim of using this technique to ...[more]

PMID: 29996777

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Dataset Information

Mapping visuospatial attention: the greyscales task in combination with repetitive navigated transcranial magnetic stimulation.

Background

Results

Publications

Mapping visuospatial attention: the greyscales task in combination with repetitive navigated transcranial magnetic stimulation.

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