Ontology highlight
ABSTRACT:
SUBMITTER: Yasuda-Yamahara M
PROVIDER: S-EPMC6042786 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Yasuda-Yamahara Mako M Rogg Manuel M Yamahara Kosuke K Maier Jasmin I JI Huber Tobias B TB Schell Christoph C
PloS one 20180712 7
Podocytes are highly-specialized epithelial cells essentially required for the generation and the maintenance of the kidney filtration barrier. This elementary function is directly based on an elaborated cytoskeletal apparatus establishing a complex network of primary and secondary processes. Here, we identify the actin-bundling protein allograft-inflammatory-inhibitor 1 like (AIF1L) as a selectively expressed podocyte protein in vivo. We describe the distinct subcellular localization of AIF1L t ...[more]