Ontology highlight
ABSTRACT:
SUBMITTER: Hida A
PROVIDER: S-EPMC6043536 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Human genome variation 20180712
Circadian rhythm sleep-wake disorders (CRSWDs) are characterized by disturbed sleep-wake patterns. We genotyped a <i>PER3</i> variable number tandem repeat (VNTR) in 248 CRSWD individuals and 925 controls and found no significant association between the VNTR and CRSWDs or morningness-eveningness (diurnal) preferences in the Japanese population. Although the VNTR has been associated with circadian and sleep phenotypes in some other populations, the polymorphism may not be a universal genetic mark ...[more]