Ontology highlight
ABSTRACT:
SUBMITTER: Haziak K
PROVIDER: S-EPMC6047126 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Haziak Karolina K Herman Andrzej Przemysław AP Wojtulewicz Karolina K Pawlina Bartosz B Paczesna Kamila K Bochenek Joanna J Tomaszewska-Zaremba Dorota D
Journal of animal science and biotechnology 20180716
<h4>Background</h4>Immune stress induced by lipopolysaccharide (LPS) influences the gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) secretion. Presence of LPS interacting Toll-like receptor (TLR) 4 in the hypothalamus may enable the direct action of LPS on the GnRH/LH secretion. So, the aim of the study was to investigate the influence of intracerebroventricular (icv) injection of TLR4 antagonist on GnRH/LH secretion in anestrous ewes during LPS-induced central inflammation. Anima ...[more]