Ontology highlight
ABSTRACT:
SUBMITTER: Josefsson A
PROVIDER: S-EPMC6047665 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Josefsson Andreas A Larsson Karin K Månsson Marianne M Björkman Jens J Rohlova Eva E Åhs Daniel D Brisby Helena H Damber Jan-Erik JE Welén Karin K
Oncotarget 20180629 50
Circulating tumor cells (CTCs) are promising biomarkers in prostate cancer (PC) because they derive from primary tumor and metastatic tissues. In this study, we used quantitative real-time PCR (qPCR) to compare the expression profiles of 41 PC-related genes between paired CTC and spinal column metastasis samples from 22 PC patients that underwent surgery for spinal cord compression. We observed good concordance between the gene expression profiles in the CTC and metastasis samples in most of the ...[more]