Ontology highlight
ABSTRACT:
SUBMITTER: Wang JC
PROVIDER: S-EPMC6050465 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Wang Ji-Chang JC Sun Xin X Ma Qiang Q Fu Gui-Feng GF Cong Long-Long LL Zhang Hong H Fan De-Fu DF Feng Jun J Lu Shao-Ying SY Liu Jian-Lin JL Li Guang-Yue GY Liu Pei-Jun PJ
Journal of cellular and molecular medicine 20180504 8
Beneficial effects of metformin on cancer risk and mortality have been proved by epidemiological and clinical studies, thus attracting research interest in elucidating the underlying mechanisms. Recently, tumour-associated macrophages (TAMs) appeared to be implicated in metformin-induced antitumour activities. However, how metformin inhibits TAMs-induced tumour progression remains ill-defined. Here, we report that metformin-induced antitumour and anti-angiogenic activities were not or only parti ...[more]