Ontology highlight
ABSTRACT:
SUBMITTER: Wang SR
PROVIDER: S-EPMC6051393 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20180515 7
As a left-handed helical structure, Z-DNA is biologically active and it may be correlated with transcription and genome stability. Until recently, it remained a significant challenge to control the B/Z-DNA transition under physiological conditions. The current study represents the first to reversibly control B/Z-DNA transition using cucurbit[7]uril-based supramolecular approach. It is demonstrated that cucurbit[7]uril can encapsulate the central butanediamine moiety [HN(CH<sub>2</sub>)<sub>4</su ...[more]