Ontology highlight
ABSTRACT:
SUBMITTER: Bacher C
PROVIDER: S-EPMC6051480 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Bächer Christian C Kihm Alexander A Schrack Lukas L Kaestner Lars L Laschke Matthias W MW Wagner Christian C Gekle Stephan S
Biophysical journal 20180701 2
We investigate the margination of microparticles/platelets in blood flow through complex geometries typical for in vivo vessel networks: a vessel confluence and a bifurcation. Using three-dimensional lattice Boltzmann simulations, we confirm that behind the confluence of two vessels, a cell-free layer devoid of red blood cells develops in the channel center. Despite its small size of roughly 1 μm, this central cell-free layer persists for up to 100 μm after the confluence. Most importantly, we s ...[more]