Ontology highlight
ABSTRACT:
SUBMITTER: Feng JJ
PROVIDER: S-EPMC6053100 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Feng Jenny J JJ Ontaneda Daniel D
Degenerative neurological and neuromuscular disease 20170201
Multiple sclerosis (MS) therapy has evolved rapidly with an increased availability of several immunomodulating therapies over the past two decades. Disease-modifying therapies have proven to be effective in treating relapse-remitting MS (RRMS). However, clinical trials involving some of the same agents for secondary-progressive and primary-progressive MS (SPMS and PPMS) have been largely negative. The pathogenesis of progressive MS remains unclear, but B-cells may play a significant role in chro ...[more]