Ontology highlight
ABSTRACT:
SUBMITTER: To KK
PROVIDER: S-EPMC6054943 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
World journal of gastroenterology 20180701 27
MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that can post-transcriptionally regulate the expression of various oncogenes and tumor suppressor genes. Dysregulated expression of many miRNAs have been shown to mediate the signaling pathways critical in the multistep carcinogenesis of colorectal cancer (CRC). MiRNAs are stable and protected from RNase-mediated degradation, thereby enabling its detection in biological fluids and archival tissues for biomarker studies. This review fo ...[more]