Ontology highlight
ABSTRACT:
SUBMITTER: Signes A
PROVIDER: S-EPMC6056720 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Signes Alba A Fernandez-Vizarra Erika E
Essays in biochemistry 20180720 3
The assembly of the five oxidative phosphorylation system (OXPHOS) complexes in the inner mitochondrial membrane is an intricate process. The human enzymes comprise core proteins, performing the catalytic activities, and a large number of 'supernumerary' subunits that play essential roles in assembly, regulation and stability. The correct addition of prosthetic groups as well as chaperoning and incorporation of the structural components require a large number of factors, many of which have been ...[more]