Ontology highlight
ABSTRACT:
SUBMITTER: Kumar Sarker S
PROVIDER: S-EPMC6057484 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Journal of advanced research 20180425
Patients with beta-thalassemia major (BTM) suffer from fatigue, poor physical fitness, muscle weakness, lethargy, and cardiac complications which are related to an energy crisis. Carnitine and acylcarnitine derivatives play important roles in fatty acid oxidation, and deregulation of carnitine and acylcarnitine metabolism may lead to an energy crisis. The present study aimed to investigate carnitine and acylcarnitine metabolites to gain an insight into the pathophysiology of BTM. Dried blood spo ...[more]