Ontology highlight
ABSTRACT:
SUBMITTER: Zou F
PROVIDER: S-EPMC6058033 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Zou Fagui F Wang Xu X Han Xinxin X Rothschild Gerson G Zheng Song Guo SG Basu Uttiya U Sun Jianbo J
Frontiers in immunology 20180718
Tetraspanins are transmembrane proteins that modulate multiple diverse biological processes, including signal transduction, cell-cell communication, immunoregulation, tumorigenesis, cell adhesion, migration, and growth and differentiation. Here, we provide a systematic review of the involvement of tetraspanins and their partners in the regulation and function of B cells, including mechanisms associated with antigen presentation, antibody production, cytokine secretion, co-stimulator expression, ...[more]