Ontology highlight
ABSTRACT:
SUBMITTER: Philley JV
PROVIDER: S-EPMC6063893 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20180727 1
Nontuberculous mycobacterial lung disease (NTM), including Mycobacterium avium complex (MAC), is a growing health problem in North America and worldwide. Little is known about the molecular alterations occurring in the tissue microenvironment during NTM pathogenesis. Utilizing next generation sequencing, we sequenced sputum and matched lymphocyte DNA in 15 MAC patients for a panel of 19 genes known to harbor cancer susceptibility associated mutations. Thirteen of 15 NTM subjects had a diagnosis ...[more]