Ontology highlight
ABSTRACT:
SUBMITTER: Xie HT
PROVIDER: S-EPMC6065236 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Xie Heng-Tao HT Xia Zhong-Yuan ZY Pan Xia X Zhao Bo B Liu Zhi-Gang ZG
Neural regeneration research 20180701 7
Puerarin is a major active ingredient of the traditional Chinese plant medicine, Radix Puerariae, and commonly used in the treatment of myocardial and cerebral ischemia. However, the effects of puerarin on neuropathic pain are still unclear. In this study, a neuropathic pain animal model was created by partial sciatic nerve ligation. Puerarin (30 or 60 mg/kg) was intraperitoneally injected once a day for 7 days. Mechanical allodynia and thermal hyperalgesia were examined at 1 day after model est ...[more]