Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Beas J
PROVIDER: S-EPMC6070677 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
López-Beas Javier J Capilla-González Vivian V Aguilera Yolanda Y Mellado Nuria N Lachaud Christian C CC Martín Franz F Smani Tarik T Soria Bernat B Hmadcha Abdelkrim A
Molecular therapy. Nucleic acids 20180615
Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this particular lineage, more effort is still required to stress the importance of developing an efficient, reproducible, easy, and cost-effective differentiation protocol to obtain more mature, homogeneous, and functional insulin-secreting cells. In addition, microRNAs (miRNAs) have emerged as a class of small non-coding RNAs that regulate many cellular processes, including pancreatic ...[more]