Ontology highlight
ABSTRACT:
SUBMITTER: Shahsavari S
PROVIDER: S-EPMC6071699 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Shahsavari Shahien S McNamara Chase C Sylvester Mark M Bromley Emily E Joslin Savannah S Lu Bao-Yuan BY Fang Shiyue S
Beilstein journal of organic chemistry 20180713
The 1,3-dithiane-based dM-Dmoc group was studied for the protection of amino groups. Protection was achieved under mild conditions for aliphatic amines, and under highly reactive conditions for the less reactive arylamines. Moderate to excellent yields were obtained. Deprotection was performed by oxidation followed by treating with a weak base. The yields were good to excellent. The new amino protecting group offers a different dimension of orthogonality in reference to the commonly used amino p ...[more]