Ontology highlight
ABSTRACT:
SUBMITTER: Gosangi M
PROVIDER: S-EPMC6072356 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Gosangi Mallikarjun M Rapaka Hithavani H Mujahid Thasneem Yoosuf TY Patri Srilakshmi V SV
MedChemComm 20170220 5
Herein, we report the synthesis, characterization and evaluation of the transfection efficiencies of a series of dicationic amphiphiles designed to construct quaternary ammonium ion-based cationic lipids varying in chain length of the hydrophobic back bone connected individually through head group to a 1,2,3-triazolium cation consisting of 2-hydroxy ethyl chain as substitution. Accordingly, three dicationic amphiphiles were synthesized by "click chemistry" approach and formulated to bilayered ve ...[more]