Polycystic Kidney Disease: Lessons Learned from Caenorhabditis elegans Mating Behavior.
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ABSTRACT:
SUBMITTER: Ward CJ
PROVIDER: S-EPMC6077978 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Publications
Polycystic Kidney Disease: Lessons Learned from Caenorhabditis elegans Mating Behavior.
Ward Christopher J CJ Sharma Madhulika M
Current biology : CB 20151201 24
Male worm mating requires lov-1 and pkd-2 (homologs of the human polycystic kidney disease genes, PKD1 and PKD2), which are expressed in male-specific neurons. Transcriptomic analysis of these neurons now catalogs molecules involved in signaling and ectosome biogenesis, with implications for human PKD. ...[more]
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