Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC6078172 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature

Bioinformatics (Oxford, England) 20150930 2
<h4>Contributions</h4>We developed a new lossless compression method for WIG data, named smallWig, offering the best known compression rates for RNA-seq data and featuring random access functionalities that enable visualization, summary statistics analysis and fast queries from the compressed files. Our approach results in order of magnitude improvements compared with bigWig and ensures compression rates only a fraction of those produced by cWig. The key features of the smallWig algorithm are st ...[more]