Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC6084452 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Wang Sha S Cebrian Cristina C Schnell Santiago S Gumucio Deborah L DL
Developmental cell 20180701 2
The early midgut undergoes intensive elongation, but the underlying cellular and molecular mechanisms are unknown. The early midgut epithelium is pseudostratified, and its nuclei travel between apical and basal surfaces in concert with cell cycle. Using 3D confocal imaging and 2D live imaging, we profiled behaviors of individual dividing cells. As nuclei migrate apically for mitosis, cells maintain a basal process (BP), which splits but is inherited by only one daughter. After mitosis, some daug ...[more]