Association of Tef polymorphism with depression in Parkinson disease.
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ABSTRACT:
SUBMITTER: Hua P
PROVIDER: S-EPMC6089252 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
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Association of Tef polymorphism with depression in Parkinson disease.
Hua Ping P Liu Weiguo W Kuo Sheng-Han SH Zhao Yanyan Y Chen Ling L Zhang Ning N Wang Chun C Guo Suwan S Wang Li L Xiao Hong H Kwan Justin Y JY Wu Tianxia T
Movement disorders : official journal of the Movement Disorder Society 20121108 13
<h4>Background</h4>Circadian rhythm disturbance has been implicated in depression, and polymorphisms of circadian genes Cry1, Cry2, and Tef are associated with depression. However, the relationship between these genes and depression symptoms in Parkinson's disease (PD) has not been established.<h4>Methods</h4>Four hundred eight subjects with PD participated in this study. Demographics, UPDRS, Mini-Mental Status Examination (MMSE), and Hamilton Rating Scale for Depression (HAMD) were obtained in ...[more]
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