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The negative effect of perioperative red blood cell transfusion on morbidity and mortality after major abdominal operations.

ABSTRACT: BACKGROUND:This study aims to test associations between perioperative blood transfusion and postoperative morbidity and mortality after major abdominal operations. METHODS:The 2014 ACS NSQIP dataset was queried for all patients who underwent one of the ten major abdominal operations. Separate multivariable regression models, were developed to evaluate the independent effects of perioperative blood transfusion on morbidity and mortality. RESULTS:Of 48,854 patients in the study cohort, 4887 (10%) received a blood transfusion. Rates of transfusion ranged from 4% for laparoscopic gastrointestinal resection to 58% for open AAA. After adjusting for significant effects of NSQIP-estimated probabilities, transfusion was independently associated with morbidity and mortality after open AAA repair (OR?=?1.99/14.4 respectively, p???0.010), esophagectomy (OR?=?2.80/3.0, p?

SUBMITTER: Elwood NR

PROVIDER: S-EPMC6097952 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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The negative effect of perioperative red blood cell transfusion on morbidity and mortality after major abdominal operations.

Elwood Nathan R NR Martin Allison N AN Turrentine Florence E FE Jones R Scott RS Zaydfudim Victor M VM

American journal of surgery 20180217 3

<h4>Background</h4>This study aims to test associations between perioperative blood transfusion and postoperative morbidity and mortality after major abdominal operations.<h4>Methods</h4>The 2014 ACS NSQIP dataset was queried for all patients who underwent one of the ten major abdominal operations. Separate multivariable regression models, were developed to evaluate the independent effects of perioperative blood transfusion on morbidity and mortality.<h4>Results</h4>Of 48,854 patients in the stu ...[more]

PMID: 29475550

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| S-EPMC6623955 | biostudies-literature

Perioperative blood transfusion in major abdominal cancer surgery: a multi-centre service evaluation and national survey.

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A novel model forecasting perioperative red blood cell transfusion.

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Transfusion of salvaged red blood cells during pancreatic ductal adenocarcinoma operations.

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The impact of perioperative red blood cell transfusion on the prognosis of colorectal cancer

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Project description: Not available

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Impact of perioperative red blood cell transfusion on the prognosis of patients with epithelial ovarian cancer.

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