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Bench-Stable N-Heterocyclic Carbene Nickel Precatalysts for C-C and C-N Bond-Forming Reactions.

ABSTRACT: Herein, we introduce a new class of bench-stable N-heterocyclic carbene (NHC) nickel-precatalysts for homogeneous nickel-catalysis. The nickel(II) complexes are readily activated to Ni⁰ in?situ under mild conditions, via a proposed Heck-type mechanism. The precatalysts are shown to facilitate carbonyl-ene, hydroalkenylation, and amination reactions.

SUBMITTER: Strieth-Kalthoff F

PROVIDER: S-EPMC6099443 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Bench-Stable N-Heterocyclic Carbene Nickel Precatalysts for C-C and C-N Bond-Forming Reactions.

Strieth-Kalthoff Felix F Longstreet Ashley R AR Weber Jessica M JM Jamison Timothy F TF

ChemCatChem 20180502 13

Herein, we introduce a new class of bench-stable N-heterocyclic carbene (NHC) nickel-precatalysts for homogeneous nickel-catalysis. The nickel(II) complexes are readily activated to Ni0 in situ under mild conditions, via a proposed Heck-type mechanism. The precatalysts are shown to facilitate carbonyl-ene, hydroalkenylation, and amination reactions. ...[more]

PMID: 30147804

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