Ontology highlight
ABSTRACT:
SUBMITTER: Gimenez D
PROVIDER: S-EPMC6099454 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20180627 33
Stability towards protease degradation combined with modular synthesis has made peptoids of considerable interest in the fields of chemical biology, medicine, and biomaterials. Given their tertiary amide backbone, peptoids lack the capacity to hydrogen-bond, and as such, controlling secondary structure can be challenging. The incorporation of bulky, charged, or chiral aromatic monomers can be used to control conformation but such building blocks limit applications in many areas. Through NMR and ...[more]