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Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids.

ABSTRACT: An environmentally-friendly and easy synthesis of a series of novel functionalized imidazolium-based ionic liquids (ILs) is described under both the conventional procedure and microwave irradiation. The structures of newly synthesized room-temperature ionic liquids (RTILs) were established by different spectral analyses. All ILs (1?14) were screened for their in vitro antimicrobial activity against a panel of clinically isolated bacteria. The results of the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) showed that some of the tested ILs are very promising anti-bacterial agents especially those containing an alkyl chain with a phenyl group (most notably 1, 2, 12, and 13).

SUBMITTER: Albalawi AH

PROVIDER: S-EPMC6099736 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids.

Albalawi Ahmed H AH El-Sayed Wael S WS Aljuhani Ateyatallah A Almutairi Saud M SM Rezki Nadjet N Aouad Mohamed R MR Messali Mouslim M

Molecules (Basel, Switzerland) 20180715 7

An environmentally-friendly and easy synthesis of a series of novel functionalized imidazolium-based ionic liquids (ILs) is described under both the conventional procedure and microwave irradiation. The structures of newly synthesized room-temperature ionic liquids (RTILs) were established by different spectral analyses. All ILs (<b>1</b>⁻<b>14</b>) were screened for their in vitro antimicrobial activity against a panel of clinically isolated bacteria. The results of the minimum inhibitory conce ...[more]

PMID: 30011951

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