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Preparation of biopolymer fibers by electrospinning from room temperature ionic liquids.


ABSTRACT: Electrospinning is a versatile process used to prepare micro- and nano- sized fibers from various polymers dissolved in volatile solvents. In this report, cellulose and cellulose-heparin composite fibers are prepared from nonvolatile room temperature ionic liquid (RTIL) solvents by electrospinning. RTILs are extracted from the biopolymer fiber after the fiber formation using a cosolvent. Micron to nanometer sized, branched fibers were obtained from 10% (w/w) concentration of polysaccharide biopolymer in RTIL solution with an applied voltage of 15-20 kV. Cellulose-heparin composite fibers showed anticoagulant activity, demonstrating that the bioactivity of heparin remained unaffected even on exposure to a high voltage involved in electrospinning.

SUBMITTER: Viswanathan G 

PROVIDER: S-EPMC4777308 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature

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Preparation of biopolymer fibers by electrospinning from room temperature ionic liquids.

Viswanathan Gunaranjan G   Murugesan Saravanababu S   Pushparaj Victor V   Nalamasu Omkaram O   Ajayan Pulickel M PM   Linhardt Robert J RJ  

Biomacromolecules 20060201 2


Electrospinning is a versatile process used to prepare micro- and nano- sized fibers from various polymers dissolved in volatile solvents. In this report, cellulose and cellulose-heparin composite fibers are prepared from nonvolatile room temperature ionic liquid (RTIL) solvents by electrospinning. RTILs are extracted from the biopolymer fiber after the fiber formation using a cosolvent. Micron to nanometer sized, branched fibers were obtained from 10% (w/w) concentration of polysaccharide biopo  ...[more]

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