Brain Network Connectivity and Executive Function in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia.
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ABSTRACT:
SUBMITTER: Kesler SR
PROVIDER: S-EPMC6103246 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Brain Network Connectivity and Executive Function in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia.
Kesler Shelli R SR Ogg Robert R Reddick Wilburn E WE Phillips Nicholas N Scoggins Matthew M Glass John O JO Cheung Yin Ting YT Pui Ching-Hon CH Robison Leslie L LL Hudson Melissa M MM Krull Kevin R KR
Brain connectivity 20180801 6
Chemotherapeutic agents used to treat acute lymphoblastic leukemia (ALL), the most common cancer affecting young children, have been associated with long-term cognitive impairments that reduce quality of life. Executive dysfunction is one of the most consistently observed deficits and can have substantial and pervasive effects on academic success, occupational achievement, psychosocial function, and psychiatric status. We examined the neural mechanisms of executive dysfunction by measuring struc ...[more]
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