Ontology highlight
ABSTRACT:
SUBMITTER: Fauquier L
PROVIDER: S-EPMC6105712 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Fauquier Lucas L Azzag Karim K Parra Marco Antonio Mendoza MAM Quillien Aurélie A Boulet Manon M Diouf Sarah S Carnac Gilles G Waltzer Lucas L Gronemeyer Hinrich H Vandel Laurence L
Scientific reports 20180822 1
The acetyltransferases CBP and P300 have been implicated in myogenesis in mouse immortalized cell lines but these studies focused only on the expression of a handful of myogenic factors. Hence, the respective role of these two related cofactors and their impact at global scale on gene expression rewiring during primary myoblast differentiation remain unknown. Here, we characterised the gene networks regulated by these two epigenetic enzymes during human primary myoblast differentiation (HPM). We ...[more]